krab domain Search Results


86
Addgene inc plasmid 156 plexatf t2a nls lexa krab mcherry lexy
Plasmid 156 Plexatf T2a Nls Lexa Krab Mcherry Lexy, supplied by Addgene inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/plasmid 156 plexatf t2a nls lexa krab mcherry lexy/product/Addgene inc
Average 86 stars, based on 1 article reviews
plasmid 156 plexatf t2a nls lexa krab mcherry lexy - by Bioz Stars, 2026-04
86/100 stars
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90
Hirasawa Works zinc finger protein 57
Zinc Finger Protein 57, supplied by Hirasawa Works, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/zinc finger protein 57/product/Hirasawa Works
Average 90 stars, based on 1 article reviews
zinc finger protein 57 - by Bioz Stars, 2026-04
90/100 stars
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90
TranScrip Partners krab domain-containing znf transcription factor avgr8
Krab Domain Containing Znf Transcription Factor Avgr8, supplied by TranScrip Partners, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/krab domain-containing znf transcription factor avgr8/product/TranScrip Partners
Average 90 stars, based on 1 article reviews
krab domain-containing znf transcription factor avgr8 - by Bioz Stars, 2026-04
90/100 stars
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90
GenScript corporation codon optimized krab domain
Codon Optimized Krab Domain, supplied by GenScript corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/codon optimized krab domain/product/GenScript corporation
Average 90 stars, based on 1 article reviews
codon optimized krab domain - by Bioz Stars, 2026-04
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90
GenScript corporation krüppel-associated box (krab) domain
a, Design of SOX2 TALE for TALE repressor screening. A TALE targeting a 14bp sequence within the SOX2 locus of the human genome was synthesized as described previously . b, List of all repressors screened and their host origin (left). Eight different candidate repressor domains were fused to the C-term of the SOX2 TALE. c, The fold decrease of endogenous SOX2 mRNA is measured using qRT-PCR by dividing the SOX2 mRNA levels in mock transfected cells by SOX2 mRNA levels in cells transfected with each candidate TALE repressor. d, Transcriptional repression of endogenous CACNA1C. TALEs using NN, NK, and NH as the G-targeting RVD were constructed to target a 18bp target site within the human CACNA1C locus (site 1 in ). Each TALE is fused to the SID repression domain. NLS, nuclear localization signal; <t>KRAB,</t> <t>Krüppel-associated</t> box; SID, mSin interaction domain. All results are collected from three independent experiments in HEK 293FT cells. Error bars indicate s.e.m.; n = 3. * p < 0.05, Student’s t test.
Krüppel Associated Box (Krab) Domain, supplied by GenScript corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/krüppel-associated box (krab) domain/product/GenScript corporation
Average 90 stars, based on 1 article reviews
krüppel-associated box (krab) domain - by Bioz Stars, 2026-04
90/100 stars
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N/A
Standard format Plasmid sent in bacteria as agar stab
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Zinc Finger With Krab And Scan Domains 3 Antibody is a Rabbit Polyclonal antibody against Zinc Finger With Krab And Scan Domains 3
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Image Search Results


a, Design of SOX2 TALE for TALE repressor screening. A TALE targeting a 14bp sequence within the SOX2 locus of the human genome was synthesized as described previously . b, List of all repressors screened and their host origin (left). Eight different candidate repressor domains were fused to the C-term of the SOX2 TALE. c, The fold decrease of endogenous SOX2 mRNA is measured using qRT-PCR by dividing the SOX2 mRNA levels in mock transfected cells by SOX2 mRNA levels in cells transfected with each candidate TALE repressor. d, Transcriptional repression of endogenous CACNA1C. TALEs using NN, NK, and NH as the G-targeting RVD were constructed to target a 18bp target site within the human CACNA1C locus (site 1 in ). Each TALE is fused to the SID repression domain. NLS, nuclear localization signal; KRAB, Krüppel-associated box; SID, mSin interaction domain. All results are collected from three independent experiments in HEK 293FT cells. Error bars indicate s.e.m.; n = 3. * p < 0.05, Student’s t test.

Journal: Nature communications

Article Title: Comprehensive Interrogation of Natural TALE DNA Binding Modules and Transcriptional Repressor Domains

doi: 10.1038/ncomms1962

Figure Lengend Snippet: a, Design of SOX2 TALE for TALE repressor screening. A TALE targeting a 14bp sequence within the SOX2 locus of the human genome was synthesized as described previously . b, List of all repressors screened and their host origin (left). Eight different candidate repressor domains were fused to the C-term of the SOX2 TALE. c, The fold decrease of endogenous SOX2 mRNA is measured using qRT-PCR by dividing the SOX2 mRNA levels in mock transfected cells by SOX2 mRNA levels in cells transfected with each candidate TALE repressor. d, Transcriptional repression of endogenous CACNA1C. TALEs using NN, NK, and NH as the G-targeting RVD were constructed to target a 18bp target site within the human CACNA1C locus (site 1 in ). Each TALE is fused to the SID repression domain. NLS, nuclear localization signal; KRAB, Krüppel-associated box; SID, mSin interaction domain. All results are collected from three independent experiments in HEK 293FT cells. Error bars indicate s.e.m.; n = 3. * p < 0.05, Student’s t test.

Article Snippet: Truncation variants of the Krüppel-associated box (KRAB) domain, the PIE-1 repression domain (PIE-1), the QA domain within the Ubx gene (Ubx-QA), the IAA28 repression domain (IAA28-RD), Tbx3 repression domain (Tbx3-RD), and the mSin interaction domain (SID) were codon optimized for mammalian expression and synthesized with flanking Nhe I and Xba I restriction sites (Genscript).

Techniques: Sequencing, Synthesized, Quantitative RT-PCR, Transfection, Construct